BackgroundIntraoperativemagneticresonanceimaging(iMRI)datesbacktothe1990sandhasbeensuccessfullyappliedinneurosurgerybuttheywerelow-fieldiMRI(1.0T).Thispaperreportstheclinicalexperiencewitha3TiMRI-integratedneurosurgicalsuiteinHuashanHospital,Shanghai,China.MethodsFromSeptember2010throughMarch2012,373consecutivepatientsunderwentneurologicalsurgeryunderguidancewith3TiMRI.Aretrospectiveanalysiswasconductedregardingclinicalefficiency.ResultsAllsurgeryinthe373patientswassafe.Theratioofgrosstotalresectionforcerebralgliomas(n=161)wasincreasedfrom55.90%to87.58%.Theratioofbenefitinextentofresectionwas39.13%.Onehundredandfiftyeightofthe161gliomapatientsaccomplishedfollow-upat3monthspostoperatively.Twentyof161patients(12.42%)sufferedfromearlymotordeficitaftersurgery.Latemotordeficitwashoweverobservedinfiveof158patients(3.16%).Twenty-oneof161patients(13.04%)hadearlyspeechdeficitandlatespeechdeficitwasonlyobservedinsixof158patients(3.8%).Theratioofgrosstotalresectionforpituitaryadenomas(n=49)wasincreasedfrom77.55%to85.71%.Theratioofbenefitinextentofresectionwas10.2%.TherewerenoiMRI-relatedadverseeventsevenforpatientswhounderwentawakecraniotomy.ConclusionThe3TiMRIintegratedneurosurgicalsuiteprovideshigh-qualityintraoperativestructuralfunctionalandfunctionalimagingforreal-timetumorresectioncontrolandaccuratefunctionalpreservation,resultinginanimprovementinmaximalsafebrainsurgery.
标签:华山医院,神经外科,磁共振